Since the 18th century, several arsenic compounds have been used as medicines, including arsenic trioxide (ATO) which is commonly prescribed in the treatment of certain types of cancer. Although they prove to be effective, no one knows how these compounds work. Now, a group of European scientists have found the answer. They identified the mechanism by which arsenic compounds can have therapeutic properties when used to treat cancer, particularly acute promyelocytic leukaemia (APL). Their work, which is partially EU-funded, was recently published in Nature Cell Biology.
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